The UCSF Fetal Treatment Center has been on the forefront of fetal treatment research since it's inception. The first open fetal surgery in the world was performed at UCSF over 2 decades ago and we continue to dedicate ourselves to research and innovation.
Studying the use of fetal surgery in the treatment of Myelomeningocele, as part of the Management of Myelomeningocele Study (MOMS)
N. Scott Adzick, M.D., Elizabeth A. Thom, Ph.D., Catherine Y. Spong, M.D., John W. Brock, III, M.D., Pamela K. Burrows, M.S., Mark P. Johnson, M.D., Lori J. Howell, R.N., M.S., Jody A. Farrell, R.N., M.S.N., Mary E. Dabrowiak, R.N., M.S.N., Leslie N. Sutton, M.D., Nalin Gupta, M.D., Ph.D., Noel B. Tulipan, M.D., Mary E. D'Alton, M.D., and Diana L. Farmer, M.D. for the MOMS Investigators. A Randomized Trial of Prenatal versus Postnatal Repair of Myelomeningocele. New England Journal of Medicine. 2011 Feb
von Koch CS, Compagnone N, Hirose S, Yoder S, Harrison MR, Farmer DL. Myelomeningocele: characterization of a surgically induced sheep model and its central nervous system similarities and differences to the human disease. Am J Obstet Gynecol. 2005 Oct;193(4):1456-62.
von Koch CS, Glenn OA, Goldstein RB, Barkovich AJ. Fetal magnetic resonance imaging enhances detection of spinal cord anomalies in patients with sonographically detected bony anomalies of the spine. J Ultrasound Med. 2005 Jun;24(6):781-9
Williams G, Coakley FV, Qayyum S, Glenn OA, Breiman RS, Callen PW. Evaluation of femur length during the second and third trimesters in fetuses with myelomeningocele. Ultrasound Obstet Gynecol. 2004 Feb;23(2):148-51.
Farmer DL, von Koch CS, Peacock WJ, Danielpour M, Gupta N, Lee H, Harrison MR. In utero repair of myelomeningocele: experimental pathophysiology, initial clinical experience, and outcomes. Arch Surg. 2003 Aug;138(8):872-8.
Study analyzing fetal surgery and preterm labor.
Study analyzing the maternal risks of fetal surgical interventions.
Golombeck K, Ball RH, Lee H, Farrell JA, Farmer DL, Jacobs VR, Rosen MA, Filly RA, Harrison MR. Maternal morbidity after maternal-fetal surgery. Am J Obstet Gynecol. 2006 Mar;194(3):834-9.
Examination of a novel preventive “presealant” to protect amniotic membranes during fetal surgery.
Cortes RA, Wagner AJ, Lee H, Clifton MS, Grethel E, Yang SH, Ball R, Harrison MR. Pre-emptive placement of a presealant for amniotic access. Am J Obstet Gynecol. 2005 Sep;193(3 Pt 2):1197-203
Study evaluting recent advances in fetal treatment.
The innovative procedures at FTC saved the lives of both Angela and Guy, whom were both diagnosed with severe CCAMs.